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Drug-induced photosensitivity Photosensitive drug reaction secondary to medications may cause phototoxic, photoallergic, and lichenoid reactions, and photodistributed telangiectasias , as well as pseudoporphyria.
Azithromycin causes QT prolongation that may cause life-threatening arrhythmias such as torsades de pointes. [11] No harm has been found with its use during pregnancy. [10] Its safety during breastfeeding is not confirmed, but it is likely safe. [12] Azithromycin is an azalide, a type of macrolide antibiotic. [10]
Sunlight, especially its ultraviolet radiation component, can cause increased or additional types of damage in predisposed individuals, such as those taking certain phototoxic drugs, or those with certain conditions associated with photosensitivity, including: Psoriasis [5] Atopic eczema [5] Mastocytosis; Mast cell activation syndrome ...
Ingested medications may cause systemic photosensitivity and topically applied medications, cosmetics and essential oils may lead to local (or perhaps systemic) photosensitivity. Para-aminobenzoic acid ( PABA ), found in some sunscreens, can also cause photosensitivity.
Photosensitivity is the amount to which an object reacts upon receiving photons, especially visible light. In medicine, the term is principally used for abnormal reactions of the skin, and two types are distinguished, photoallergy and phototoxicity .
Phototoxicity, also called photoirritation, is a chemically induced skin irritation, requiring light, that does not involve the immune system. [1] It is a type of photosensitivity. [1] [2] The skin response resembles an exaggerated sunburn.
It increases the risk of sunburn under exposure to light from the sun or other sources. This may be of particular importance for those intending to take on vacations long-term doxycycline as a malaria prophylaxis. They may cause stomach or bowel upsets, and, on rare occasions, allergic reactions.
PLE does not increase the risk of lupus. [15] Other similar appearing conditions are solar urticaria, which has a shorter duration, the eczema-like condition, photosensitive dermatitis, [2] and photosensitivity drug reaction. [9] Prickly heat, which is caused by warm weather or heat is not the same as PLE. [5]
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