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Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject covers topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics and epigenetics on neuronal development, and the molecular basis for neuroplasticity and ...
The first biochemical pathology test for any brain disease can be attributed to Vito Maria Buscaino (1887-1978), a neuropsychiatrist who studied schizophrenia. He found that treating her patients' urine who had schizophrenia, extrapyramidal disorders, or amentia, with 5% silver nitrate produced a black precipitate linked with an abnormal level ...
The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the DNA-binding domain (DBD or often also abbreviated as BD) and activating domain (AD).
Molecular neuroscience is a branch of neuroscience that examines the biology of the nervous system with molecular biology, molecular genetics, protein chemistry and related methodologies (ie. concerning neurotransmitters moving via physiology of synapses etc) Neurochemistry; Nutritional neuroscience; Neuropeptide [ also see Neuropharmacology above]
Molecular diagnostics uses in vitro biological assays such as PCR-ELISA or Fluorescence in situ hybridization. [19] [20] The assay detects a molecule, often in low concentrations, that is a marker of disease or risk in a sample taken from a patient.
Neurons communicate with one another via synapses. Synapses are specialized junctions between two cells in close apposition to one another. In a synapse, the neuron that sends the signal is the presynaptic neuron and the target cell receives that signal is the postsynaptic neuron or cell. Synapses can be either electrical or chemical.
The added two graduate schools are the school of Cellular and Molecular Neuroscience and the school of Neural Information Processing. These schools differ from the behaviour- and systems-oriented first graduate school by focusing on the cell and molecular level and on theoretical neuroscience, respectively.
Cellular and Molecular Neurobiology is a peer-reviewed scientific journal covering neuroscience, especially at the cellular and subcellular levels. It was established in 1981 and is published by Springer Science+Business Media. The editor-in-chief is Juan M. Saavedra (Georgetown University).