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Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject covers topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics and epigenetics on neuronal development, and the molecular basis for neuroplasticity and ...
The first biochemical pathology test for any brain disease can be attributed to Vito Maria Buscaino (1887-1978), a neuropsychiatrist who studied schizophrenia. He found that treating her patients' urine who had schizophrenia, extrapyramidal disorders, or amentia, with 5% silver nitrate produced a black precipitate linked with an abnormal level ...
Molecular neuroscience is a branch of neuroscience that examines the biology of the nervous system with molecular biology, molecular genetics, protein chemistry and related methodologies (ie. concerning neurotransmitters moving via physiology of synapses etc) Neurochemistry; Nutritional neuroscience; Neuropeptide [ also see Neuropharmacology above]
Reduction in the levels of neuroligins 1, 2 and 3 results in a strong reduction of inhibitory input but little reduction in excitatory input. [14] In addition, Neuroligins interacts with PSD-95 , an intracellular protein that anchors synaptic proteins in the post-synaptic density of excitatory synapses, and gephyrin , the respective scaffolding ...
Several techniques such as intracellular recording, patch-clamp, and voltage-clamp technique, pharmacology, confocal imaging, molecular biology, two photon laser scanning microscopy and Ca 2+ imaging have been used to study activity at the cellular level. Cellular neuroscience examines the various types of neurons, the functions of different ...
According to the definition established in 2013 by Society for Brain Mapping and Therapeutics (SBMT), brain mapping is specifically defined, in summary, as the study of the anatomy and function of the brain and spinal cord through the use of imaging, immunohistochemistry, molecular & optogenetics, stem cell and cellular biology, engineering ...
Alpha-synuclein is a synuclein protein primarily found in neural tissue, making up as much as one percent of all proteins in the cytosol of brain cells. [17] It is expressed highly in neurons within the frontal cortex, hippocampus, striatum, and olfactory bulb, [17] but can also be found in the non-neuronal glial cells. [18]
Cellular and Molecular Neurobiology is a peer-reviewed scientific journal covering neuroscience, especially at the cellular and subcellular levels. It was established in 1981 and is published by Springer Science+Business Media. The editor-in-chief is Juan M. Saavedra (Georgetown University).