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Glycine acts primarily as an agonist of the glycine receptor, which is a ligand-gated chloride channel in neurons located in the spinal cord and in the brain. This chloride channel allows the negatively charged chloride ions into the neuron, causing a hyperpolarization which pushes the membrane potential further from threshold.
Glycine is also an inhibitory neurotransmitter [9] – interference with its release within the spinal cord (such as during a Clostridium tetani infection) can cause spastic paralysis due to uninhibited muscle contraction. [10] It is the only achiral proteinogenic amino acid. [11]
Ionizing radiation may be used to treat other cancers, but this may, in some cases, induce a second form of cancer. [74] Radiation can cause cancer in most parts of the body, in all animals, and at any age, although radiation-induced solid tumors usually take 10–15 years, and can take up to 40 years, to become clinically manifest, and ...
“Skin cancer is the most common cancer in the U.S., and unprotected exposure to the sun’s harmful ultraviolet rays is a major risk factor for skin cancer,” the AAD stresses in its official ...
The World Health Organization has identified glyphosate as "possibly carcinogenic to humans" and a study published earlier this year showed that glyphosate raised the cancer risk of those exposed ...
Glycine encephalopathy is a rare autosomal recessive disorder of glycine metabolism. After phenylketonuria, glycine encephalopathy is the second most common disorder of amino acid metabolism. The disease is caused by defects in the glycine cleavage system, an enzyme responsible for glycine catabolism. There are several forms of the disease ...
There is no antidote for strychnine poisoning. [5] Strychnine poisoning demands aggressive management with early control of muscle spasms, intubation for loss of airway control, toxin removal (decontamination), intravenous hydration and potentially active cooling efforts in the context of hyperthermia as well as hemodialysis in kidney failure (strychnine has not been shown to be removed by ...
Breast cancer is a rarity for men — roughly 1 out of 100,000 males get the potentially killer disease. Joe Polcaro Polcaro had noticed blood spots on a shirt from his own chest area two weeks ...