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As with many operations, allotransplantation risks some side effects. A limiting factor in tissue allotransplantation for reconstructive surgery deals with the side effects of immunosuppression (metabolic disorders, malignancies, opportunistic infections) which is a predominant issue. The risk of transmitting infection is high.
The practice of tissue transplantation dates back to 1600 BC and has undergone vast advancements since then. The four main types of tissue transplantation are xenotransplantation, allotransplantation, isotransplantation and autotransplantation, while the common tissues transplanted include skin, bone, corneal and vessel grafts. [3]
Xenotransplantation (xenos-from the Greek meaning "foreign" or strange [1] [2]), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. [3] Such cells, tissues or organs are called xenografts or xenotransplants .
However, xenotransplantation is often an extremely dangerous type of transplant because of the increased risk of non-functional compatibility, rejection, and disease carried in the tissue. In the opposite direction, attempts are being made to devise a way to transplant human fetal hearts and kidneys into animals for future transplantation into ...
It is contrasted with allotransplantation (from other individual of the same species), syngeneic transplantation (grafts transplanted between two genetically identical individuals of the same species) and xenotransplantation (from other species).
Nerve xenotransplantation means tissue transplanted between two different species. This technique is not often used. Nerve allotransplantation is the transplantation of a nerve to a receiver from a genetically non-identical donor of the same species.
allogeneic, referring to allotransplantation or an allograft (from other individual of same species). xenogeneic , referring to xenotransplantation or a xenograft (from other species). References
The porcine (or pig) heart is most similar to the human heart, and therefore represents the best anatomical fit for replacement. Implantation of a porcine valve is a type of Xenotransplantation, or Xenograft, which means a transplant from one species (in this case a pig) to another. There are some risks associated with a Xenograft such as the ...