Ad
related to: high dose antioxidant supplementsebay.com has been visited by 1M+ users in the past month
Search results
Results from the WOW.Com Content Network
Antioxidants, when consumed in isolated, high amounts, can sometimes interfere with the body's normal cellular processes, leading to unintended adverse effects rather than the desired health benefits.
High-dose supplements of antioxidants may be linked to health risks in some cases, including higher mortality rates. For example, high doses of beta-carotene and vitamin E was found to increase the risk of lung cancer and overall mortality in smokers. [2] High doses of vitamin E may increase risks of prostate cancer and one type of stroke.
High doses of some antioxidants may have harmful long-term effects. The Beta-Carotene and Retinol Efficacy Trial (CARET) study of lung cancer patients found that smokers given supplements containing beta-carotene and vitamin A had increased rates of lung cancer. [140] Subsequent studies confirmed these adverse effects. [141]
The US Food and Nutrition Board set a tolerable upper intake level (UL) at 1,000 mg (1,500 IU) per day derived from animal models that demonstrated bleeding at high doses. [30] In the US, the popularity for vitamin E as a dietary supplement peaked around 2000, with popular doses of 400, 800 and 1000 IU/day.
It can be safe to take ashwagandha supplements daily at the dosage recommended by your doctor, the experts say. Research suggests ashwagandha is well-tolerated for up to three months, per the NIH.
Vitamin C megadosage is a term describing the consumption or injection of vitamin C (ascorbic acid) in doses well beyond the current United States Recommended Dietary Allowance of 90 milligrams per day, and often well beyond the tolerable upper intake level of 2,000 milligrams per day. [1]
Reviews list trials with doses as high as 24 grams per day. [127] Concerns about possible adverse effects are that intravenous high-dose vitamin C leads to a supraphysiological level of vitamin C followed by oxidative degradation to dehydroascorbic acid and hence to oxalate, increasing the risk of oxalate kidney stones and oxalate nephropathy.
The use of antioxidants to prevent some diseases is controversial. [59] In a high-risk group like smokers, high doses of beta carotene increased the rate of lung cancer since high doses of beta-carotene in conjunction of high oxygen tension due to smoking results in a pro-oxidant effect and an antioxidant effect when oxygen tension is not high.
Ad
related to: high dose antioxidant supplementsebay.com has been visited by 1M+ users in the past month