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The history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins that became the first widely used antibiotics. Following the production of a relatively pure compound in 1942, penicillin was the first naturally-derived antibiotic.
The work on penicillin at St Mary's ended in 1929. In 1939, a team of scientists at the Sir William Dunn School of Pathology at the University of Oxford, led by Howard Florey that included Edward Abraham, Ernst Chain, Norman Heatley and Margaret Jennings, began researching penicillin. They devised a method for cultivating the mould, as well as ...
Ernest Duchesne (30 May 1874 – 12 April 1912) was a French physician who noted that certain molds kill bacteria.He made this discovery 32 years before Alexander Fleming discovered the antibiotic properties of penicillin, a substance derived from those molds, but his research went unnoticed.
Penicillin G is destroyed by stomach acid, so it cannot be taken by mouth, but doses as high as 2.4 g can be given (much higher than penicillin V). It is given by intravenous or intramuscular injection. It can be formulated as an insoluble salt, and there are two such formulations in current use: procaine penicillin and benzathine ...
The history of public health in the United states studies the US history of public health roles of the medical and nursing professions; scientific research; municipal sanitation; the agencies of local, state and federal governments; and private philanthropy. It looks at pandemics and epidemics and relevant responses with special attention to ...
Granville Raymond Rettew (April 19, 1903 – June 24, 1973), known as G. Raymond Rettew, was an American chemist and mushroom spawn cultivator from Pennsylvania who pioneered the mass production of penicillin, the world’s first antibiotic. His methods helped save the lives of tens of thousands of wounded American and Allied troops during ...
In the 1940s, she played a pertinent role in the cure for the fatal scarlet fever epidemic and other diseases that soldiers in World War II were getting. [1] Johnson was the only African American, nurse, and laboratory technician that worked on the U.S. Army Medical Corp penicillin project at the University of Minnesota. [1]
1942 – benzylpenicillin, the first penicillin; 1942 – gramicidin S, the first peptide antibiotic; 1942 – sulfadimidine; 1943 – sulfamerazine; 1944 – streptomycin, the first aminoglycoside [2] 1947 – sulfadiazine; 1948 – chlortetracycline, the first tetracycline; 1949 – chloramphenicol, the first amphenicol [2] 1949 – neomycin