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The Jackson Labs DO (Diversity Outbred) project [30] is a mouse breeding program using multiple inbred founder strains to create a genetically diverse population of mice for use in scientific research. These mice are designed for fine genetic mapping, and capture a large portion of the genetic diversity of the mouse genome. [31] This project ...
The concepts of T-mazes are used to assess rodent behavior. The different tasks such as left-right discrimination and forced alternation are mainly used with rodents to test reference and working memory. Maze research is used to show how the rodent's behavior evolves with alternate strategies to do different tasks.
Rodents, mice and rats, have been the most prominent model organism since the discovery of modern neurons by Santiago Ramon y Cajal. Rodents have a very similar architecture and a complex nervous system with very little regenerative capacity similar to that found in humans. For that reason, rodents have been heavily used in pre-clinical testing.
Laboratory rats are frequently subject to dissection or microdialysis to study internal effects on organs and the brain, such as for cancer or pharmacological research. Laboratory rats not sacrificed may be euthanized or, in some cases, become pets. Deprivation of REM sleep using the flowerpot technique
The term rat is also used in the names of other small mammals that are not true rats. Examples include the North American pack rats (aka wood rats [3]) and a number of species loosely called kangaroo rats. [3] Rats such as the bandicoot rat (Bandicota bengalensis) are murine rodents related to true rats but are not members of the genus Rattus ...
The human brain contains 86 billion neurons, with 16 billion neurons in the cerebral cortex. [ 2 ] [ 1 ] Neuron counts constitute an important source of insight on the topic of neuroscience and intelligence : the question of how the evolution of a set of components and parameters (~10 11 neurons, ~10 14 synapses) of a complex system leads to ...
Doritos are a revered snack for many. Now, scientists have found one of the ingredients in the triangle-shaped tasty tortilla chips has a superpower – it can make the skin of mice transparent.
Fortrea primate-testing lab, Vienna, Virginia, 2004–05. Most of the NHPs used are one of three species of macaques, accounting for 79% of all primates used in research in the UK, and 63% of all federally funded research grants for projects using primates in the U.S. [25] Lesser numbers of marmosets, tamarins, spider monkeys, owl monkeys, vervet monkeys, squirrel monkeys, and baboons are used ...