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Occult macular dystrophy (OMD) is a rare inherited degradation of the retina, characterized by progressive loss of function in the most sensitive part of the central retina , the location of the highest concentration of light-sensitive cells (photoreceptors) but presenting no visible abnormality.
Scanning laser ophthalmoscopy developed as a method to view a distinct layer of the living eye at the microscopic level. The use of confocal methods to diminish extra light by focusing detected light through a small pinhole made possible the imaging of individual layers of the retina with greater distinction than ever before. [4]
Ocular OCT retinal thickness map, right eye Time-domain OCT of the macular area of a retina at 800 nm, axial resolution 3 μm Spectral-domain OCT macula cross-section scan. Optical coherence tomography (OCT) is a technique for obtaining sub-surface images of translucent or opaque materials at a resolution equivalent to a low-power microscope.
Medical optical imaging is the use of light as an investigational imaging technique for medical applications, pioneered by American Physical Chemist Britton Chance.Examples include optical microscopy, spectroscopy, endoscopy, scanning laser ophthalmoscopy, laser Doppler imaging, optical coherence tomography, and transdermal optical imaging.
Observes a larger retinal field at any one time compared with ophthalmoscopy; Dilation not required, making it a less invasive procedure than traditional methods; High patient compliance; Images can be saved and used at a later time or by different clinicians; Progression of diseases can be monitored over time, allowing for better management plans
A short scan time prevents too much patient movement during signal acquisition. With the development of Fourier-domain OCT, spectral-domain OCT, and swept source signal acquisition time was greatly improved making OCTA possible. [40] OCTA scan time is now around three seconds, however, saccadic eye movement still causes a low signal-to-noise ratio.
The Heidelberg Retinal Tomography is a diagnostic procedure used in ophthalmology. The Heidelberg Retina Tomograph (HRT) is an ophthalmological confocal point scanning laser ophthalmoscope [ 1 ] for examining the cornea and certain areas of the retina using different diagnostic modules (HRT retina, HRT cornea, HRT glaucoma).
Baseline color and black and white red-free filtered images are taken prior to injection. The black and white images are filtered red-free (a green filter) to increase contrast and often gives a better image of the fundus than the color image. A 6-second bolus injection of 2-5 cc of sodium fluorescein into a vein in the arm or hand