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Minoxidil is a medication used for the treatment of high blood pressure and pattern hair loss. [5] [6] [7] It is an antihypertensive and a vasodilator. [10] It is available as a generic medication by prescription in oral tablet form and over-the-counter as a topical liquid or foam. [8] [9] [11] [12]
A 2023 study comparing the efficacy and safety of 1-milligram daily oral minoxidil and 5% topical minoxidil found that topical minoxidil had a better therapeutic effect (meaning it worked a little ...
A 2021 study gave 90 men with male pattern baldness 5% minoxidil, 10% minoxidil or a placebo. The men took the treatment for 36 weeks. The men took the treatment for 36 weeks.
Minoxidil can also negatively interact with alcohol and lower your blood pressure. Additionally, it may not be safe to use minoxidil, even at a low dose, if you have: Congestive heart failure
Minoxidil sulfate, also known as minoxidil sulfate ester or minoxidil N-O-sulfate, is an active metabolite of minoxidil (Rogaine, Loniten, others) and is the active form of this agent. [ 1 ] [ 2 ] Minoxidil acts as a prodrug of minoxidil sulfate. [ 1 ]
Out of more than 900 men that participated in one study, fewer than 40 experienced any adverse effects from topical minoxidil, with none of the side effects classified as serious.
In the 428-person study, 59 percent of men with pattern hair loss who used minoxidil on its own and 80.5 percent of men who used finasteride showed improvements after 12 months.
In its early days, before this topical treatment was developed and promoted as a mainstream hair loss treatment, minoxidil was developed as a treatment for hypertension (high blood pressure).