Ads
related to: c diff pcr vs toxinperfectfaqs.com has been visited by 100K+ users in the past month
assistantking.com has been visited by 10K+ users in the past month
consumerpie.com has been visited by 10K+ users in the past month
Search results
Results from the WOW.Com Content Network
There are different plasmid sizes of C. difficile. The detected molecular weights range from 2.7x10 6 to 100x10 6, but plasmid sizes show no correlation with toxicity. In order to detect the toxin B level in C. difficile, clinicians extensively use cell culture assays derived from stool specimens from patients with PMC.
Without either toxin A or toxin B, C. difficile may colonize the gut, but is unlikely to cause pseudomembranous colitis. [45] The colitis associated with severe infection is part of an inflammatory reaction, with the "pseudomembrane" formed by a viscous collection of inflammatory cells, fibrin , and necrotic cells.
The toxins function by damaging the intestinal mucosa and cause the symptoms of C. difficile infection, including pseudomembranous colitis. TcdA is one of the largest bacterial toxins known. With a molecular mass of 308 kDa, it is usually described as a potent enterotoxin , [ 3 ] but it also has some activity as a cytotoxin . [ 4 ]
Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. [4] [5] It is known also as C. difficile, or C. diff (/ s iː d ɪ f /), and is a Gram-positive species of spore-forming bacteria. [6]
PCR is effective when the gene of a known enzyme for producing the microbial toxin or the microbial toxin itself is known. [16] One type of PCR is real time PCR also called quantitative PCR. [ 20 ] This type of PCR uses fluorescence and then does an analysis by measuring the amount of fluorescence that reflects the DNA sample more specifically ...
The Ccd and parD systems are found to be strikingly similar in terms of their structures and actions. The antitoxin protein of each system interacts with its cognate toxin to neutralise the activity of the toxin and in the process the complex of the two becomes an efficient transcription repressor. [6]
Ads
related to: c diff pcr vs toxinperfectfaqs.com has been visited by 100K+ users in the past month
assistantking.com has been visited by 10K+ users in the past month
consumerpie.com has been visited by 10K+ users in the past month