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In analytical chemistry, the detection limit, lower limit of detection, also termed LOD for limit of detection or analytical sensitivity (not to be confused with statistical sensitivity), is the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%).
There are different definitions within laboratory quality control, wherein "analytical sensitivity" is defined as the smallest amount of substance in a sample that can accurately be measured by an assay (synonymously to detection limit), and "analytical specificity" is defined as the ability of an assay to measure one particular organism or ...
A minimum detectable signal is a signal at the input of a system whose power allows it to be detected over the background electronic noise of the detector system. It can alternately be defined as a signal that produces a signal-to-noise ratio of a given value m at the output.
Threshold limit value − time-weighted average (TLV-TWA): The average exposure on the basis of a 8 hours per day, 40 hours per week work schedule. Threshold limit value − short-term exposure limit (TLV-STEL): A 15-minute TWA exposure that should not be exceeded at any time during a workday, even if the 8-hour TWA is within the TLV-TWA.
Considering detection limit, both TCD and FID reach low concentration levels (inferior to ppm or ppb). [ 2 ] Both of them require pressurized carrier gas (Typically: H 2 for FID, He for TCD) but due to the risk associated with storing H 2 (high flammability, see Hydrogen safety ), TCD with He should be considered in locations where safety is ...
An example might be a cohort study into cumulative exposure to arsenic from drinking water, whereby the mortality rates due to a number of cancers in a highly exposed group (which drinks water with a mean arsenic concentration of, say 10 mg) is compared with those in the general population.
An occupational exposure limit is an upper limit on the acceptable concentration of a hazardous substance in workplace air for a particular material or class of materials. It is typically set by competent national authorities and enforced by legislation to protect occupational safety and health .
A clinical researcher might report: "in my own experience treatment X does not do well for condition Y". [ 3 ] [ 4 ] The use of a P value cut-off point of 0.05 was introduced by R.A. Fisher; this led to study results being described as either statistically significant or non-significant. [ 5 ]