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Polyhexamethylene guanidine (PHMG) is a guanidine derivative that is used as a biocidal disinfectant, often in the form of its salt polyhexamethylene guanidine phosphate (PHMG-P). Studies have shown that PHMG in solution has fungicidal as well as bactericidal activity against both Gram-positive and Gram-negative bacteria . [ 2 ]
The main cause of the lung diseases was the chemicals PHMG, methylchloroisothiazolinone (CMIT), methylisothiazolinone (MIT) and oligo(2-(2-ethoxy)-ethoxyethyl)guanidinium-chloride (PGH). [3] Experiments by the South Korean government found pulmonary toxicity of PHMG and PGH when inhaled as a vapor.
Products containing PHMB are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions ...
In 1998, PHMG was founded as PleaseHoldUK in Chester, England.Its office relocated to Manchester in 2000, where the global headquarters has been based since. The agency has rebranded several times. PleaseHoldUK became PH Media Group in 2008, before transitioning to PHMG in 2016. Following significant growth into new territories, the company underwent its most recent
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Great Lakes Chemical Company was founded in Michigan in 1936 to extract bromine from underground salt water brine deposits. It was acquired by McClanahan Oil in 1948 and rechristened Great Lakes Oil and Chemical Company, but by 1960 the company had moved away from oil and gas, instead focusing on the research and production of bromine-based chemicals.
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