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Adolescents and young adults are at particular risk of meningococcal disease while the elderly are at particular risk of pneumococcal disease. People all over the world are at risk of meningitis. The highest burden of disease is seen in a region of sub-Saharan Africa, known as the African Meningitis Belt, especially recognised to be at high ...
Meningococcal disease is potentially fatal and is a medical emergency. Admission to a hospital or health centre is necessary and appropriate antibiotic treatment must be started as soon as possible. Appropriate antibiotic treatment must be started as soon as possible, ideally after the lumbar puncture has been carried out if such a puncture can ...
Annexes to the WHO Recommendations on the Use of Multivalent Meningococcal Conjugate Vaccines in Countries of the African Meningitis Belt Grading of scientific evidence (efficacy of single dose in immunocompetent children 9 to 24 months)
Meningococcal disease is a contagious disease caused by the meningococcus (Neisseria meningitidis), a Gram-negative bacterium. There are two clinical forms of meningococcal disease. Meningococcal meningitis is the more common entity, especially during epidemics; outcome is good if appropriately treated. In contrast, meningococcal septicaemia ...
Prevention of meningococcal cases and outbreaks, through vaccination, is the best control strategy. Licensed vaccines against meningococcal disease have been available for more than 50 years. Vaccines are serogroup specific and the protection they confer is of varying duration, dependent on which type is used. While there have been major improvements in strain coverage and vaccine availability ...
Meningococcal disease is potentially fatal and is a medical emergency. Admission to a hospital or health centre is necessary and appropriate antibiotic treatment must be started as soon as possible. Appropriate antibiotic treatment must be started as soon as possible, ideally after the lumbar puncture has been carried out if such a puncture can ...
Meningococcal meningitis remains a public health concern with a high case fatality rate and leading to serious long-term complications. Preventing meningitis through vaccination is the most effective way to reduce the burden and impact of the disease by delivering long-lasting protection.
WHO suggested invasive meningococcal outbreak case definition Suspected case any person with sudden onset of fever (>38.5°C rectal or 38.0°C axillary), neck stiffness, OR other meningeal signs (including bulging fontanelle in infants).
The new pentavalent meningitis vaccine builds on those that came before it: a monovalent meningococcal conjugate vaccine against serogroup A, MenACV, started rolling out in 2010. It led to the control of meningitis A in the meningitis belt and its virtual elimination. The last case of meningitis A in the belt was confirmed in 2017.
Between 1 October 2022 and 16 April 2023, Nigeria reported a total of 1686 suspected cases of meningitis, including 124 deaths, for a case fatality ratio (CFR) of 7%. Meningitis is a serious infection of the meninges, the membranes covering the brain and spinal cord. It is a devastating disease and a major public health challenge. Neisseria meningitidis (meningococcus), Streptococcus ...