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  2. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Metformin has acid dissociation constant values (pK a) of 2.8 and 11.5, so it exists very largely as the hydrophilic cationic species at physiological pH values. The metformin pK a values make it a stronger base than most other basic medications with less than 0.01% nonionized in blood.

  3. Median price ratio - Wikipedia

    en.wikipedia.org/wiki/Median_price_ratio

    The median price ratio (MPR) is the ratio given by dividing the median local unit price of a medication by the median international reference unit price, usually from the International Medical Products Price Guide. [3]: 220 [1] This measure was created in 2003 by the Health Action International (HAI) and World Health Organization (WHO) as a ...

  4. Henderson–Hasselbalch equation - Wikipedia

    en.wikipedia.org/wiki/Henderson–Hasselbalch...

    The Henderson–Hasselbalch equation relates the pH of a solution containing a mixture of the two components to the acid dissociation constant, K a of the acid, and the concentrations of the species in solution. [6] Simulated titration of an acidified solution of a weak acid (pK a = 4.7) with alkali

  5. Protein pKa calculations - Wikipedia

    en.wikipedia.org/wiki/Protein_pKa_calculations

    The pH-dependence of the activity displayed by enzymes and the pH-dependence of protein stability, for example, are properties that are determined by the pK a values of amino acid side chains. The p K a values of an amino acid side chain in solution is typically inferred from the p K a values of model compounds (compounds that are similar to ...

  6. Sitagliptin/metformin - Wikipedia

    en.wikipedia.org/wiki/Sitagliptin/metformin

    In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...

  7. 15 Alternatives to Ozempic for Weight Loss - AOL

    www.aol.com/15-alternatives-ozempic-weight-loss...

    Ozempic, and weight loss drugs like Ozempic, are often not covered by insurance and the price tag for brand name Ozempic can be around $900 to $1,000 a month. Shortages.

  8. List of syrups - Wikipedia

    en.wikipedia.org/wiki/List_of_syrups

    Golden syrup – or light treacle (also known as "Refiner's Syrup"), is a thick amber-colored form of inverted sugar syrup made in the process of refining sugar cane or sugar beet juice into sugar, or by treatment of a sugar solution with acid. Gomme syrup, or gum syrup – sugar syrup thickened with gum arabic, [5] but some recipes are plain ...

  9. WHO warns of falsified cough syrup ingredients seized in Pakistan

    www.aol.com/news/warns-falsified-cough-syrup...

    The batch of Benylin Paediatric syrup recalled was made by J&J in South Africa in May 2021, although Kenvue now owns the brand after a spin-off from J&J last year. (Reporting by Patrick Wingrove.

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