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The cause of the fevers is often a viral illness. [1] The likelihood of a febrile seizure is related to how high the temperature reaches. [1] [6] Some feel that the rate of increase is not important [1] while others feel the rate of increase is a risk factor. [17] This latter position has not been proven. [17]
Hyperthermia is generally diagnosed by the combination of unexpectedly high body temperature and a history that supports hyperthermia instead of a fever. [2] Most commonly this means that the elevated temperature has occurred in a hot, humid environment (heat stroke) or in someone taking a drug for which hyperthermia is a known side effect ...
On the other hand, a "normal" temperature may be a fever, if it is unusually high for that person; for example, medically frail elderly people have a decreased ability to generate body heat, so a "normal" temperature of 37.3 °C (99.1 °F) may represent a clinically significant fever.
Children (under the age of 18 years old) have a lower heat tolerance compared to adults due to decreased homeostatic regulatory systems, increased metabolic rates, and decreased cardiac output. [22] Strenuous exercise in high-temperature conditions is the leading cause of heat-related illness in children.
Kawasaki disease (also known as mucocutaneous lymph node syndrome) is a syndrome of unknown cause that results in a fever and mainly affects children under 5 years of age. [6] It is a form of vasculitis , in which medium-sized blood vessels become inflamed throughout the body. [ 1 ]
Chills is a feeling of coldness occurring during a high fever, but sometimes is also a common symptom which occurs alone in specific people. It occurs during fever due to the release of cytokines and prostaglandins as part of the inflammatory response, which increases the set point for body temperature in the hypothalamus.
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High doses of benzodiazepines or barbiturates are often used, with care taking place in the intensive care unit. [2] A ketogenic diet may help in some cases. [1] The medications anakinra or tocilizumab have been tried. [2] The risk of death, despite treatment is about 12%. [2] The condition newly affects about one in a million children per year ...