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  2. Fabry disease - Wikipedia

    en.wikipedia.org/wiki/Fabry_disease

    Fabry disease is sometimes diagnosed using a blood test that measures the activity of the affected enzyme called alpha-galactosidase, but genetic testing is also sometimes used, particularly in females. The treatment for Fabry disease varies depending on the organs affected by the condition, and the underlying cause can be addressed by ...

  3. Sex linkage - Wikipedia

    en.wikipedia.org/wiki/Sex_linkage

    There are fewer X-linked dominant conditions than X-linked recessive, because dominance in X-linkage requires the condition to present in females with only a fraction of the reduction in gene expression of autosomal dominance, since roughly half (or as many as 90% in some cases) of a particular parent's X chromosomes are inactivated in females.

  4. XY sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XY_sex-determination_system

    The idea is instead of having a simplistic mechanism by which you have pro-male genes going all the way to make a male, in fact there is a solid balance between pro-male genes and anti-male genes and if there is a little too much of anti-male genes, there may be a female born and if there is a little too much of pro-male genes then there will ...

  5. Sex-determination system - Wikipedia

    en.wikipedia.org/wiki/Sex-determination_system

    In some species, there are hermaphrodites, i.e., individuals that can function reproductively as either female or male. [2] There are also some species in which only one sex is present, temporarily or permanently. This can be due to parthenogenesis, the act of a female reproducing without fertilization.

  6. Maternal effect - Wikipedia

    en.wikipedia.org/wiki/Maternal_effect

    In genetics, a maternal effect occurs when the phenotype of an organism is determined by the genotype of its mother. [1] For example, if a mutation is maternal effect recessive, then a female homozygous for the mutation may appear phenotypically normal, however her offspring will show the mutant phenotype, even if they are heterozygous for the mutation.

  7. Human genetics - Wikipedia

    en.wikipedia.org/wiki/Human_genetics

    Human genetics is the study of inheritance as it occurs in human beings.Human genetics encompasses a variety of overlapping fields including: classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population genetics, developmental genetics, clinical genetics, and genetic counseling.

  8. Genetic incompatibility - Wikipedia

    en.wikipedia.org/wiki/Genetic_incompatibility

    Genetic incompatibility describes the process by which mating yields offspring that are nonviable, prone to disease, or genetically defective in some way. In nature, animals can ill afford to devote costly resources for little or no reward, ergo, mating strategies have evolved to allow females to choose or otherwise determine mates which are more likely to result in viable offspring.

  9. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...