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  2. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]

  3. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.

  4. 5 symptoms men over 40 should never ignore - AOL

    www.aol.com/finance/5-symptoms-men-over-40...

    An online survey conducted by the Cleveland Clinic of 1,174 men 18 years or older, ... Here are five symptoms that should prompt men to visit a doctor. 1. Unexplained fatigue.

  5. Ibuprofen - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen

    The correlation between the severity of symptoms and measured ibuprofen plasma levels is weak. Toxic effects are unlikely at doses below 100 mg/kg, but can be severe above 400 mg/kg (around 150 tablets of 200 mg units for an average adult male); [47] however, large doses do not indicate the clinical course is likely to be lethal. [48]

  6. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    NSAID identification on label of generic ibuprofen, an over-the-counter non-steroidal anti-inflammatory drug. Non-steroidal anti-inflammatory drugs [1] [3] (NSAID) [1] are members of a therapeutic drug class which reduces pain, [4] decreases inflammation, decreases fever, [1] and prevents blood clots.

  7. Dog Trainer Explains How to Tell if Your Dog Is Too Cold ...

    www.aol.com/dog-trainer-explains-tell-dog...

    Small, short-haired, older, or less energetic dogs are more sensitive. Some dog breeds, like Dachshunds, Greyhounds, and Whippets tend to be sensitive to lower temperatures because they lack body ...

  8. Ibuprofen/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen/paracetamol

    Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic. [6] It is available as a generic medication. [9] [10] [11]

  9. The cast of “Friends” is well known for being besties, but that developed over time. During an appearance on Dax Shepard’s “Armchair Expert” podcast, “Friends” star Lisa Kudrow ...