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The three main active ingredients in Neosporin are neomycin sulfate, polymyxin B sulfate, and bacitracin zinc. [ 20 ] [ 7 ] One of the main components is neomycin sulfate, which is a type of antibiotic discovered in 1949 by microbiologist Selman Waksman at Rutgers University. [ 21 ]
Nitrofurazone is indicated for topical use in dogs, cats, and horses, for the treatment or prophylactic treatment of superficial bacterial infections, burns, and cutaneous ulcers. [9] Preparations for treating infections, such as fin rot , in ornamental fish are also still commercially available.
A wry Letterman will sometimes advise an inattentive Kalter to use a medication normally used for more mild injuries including Neosporin or Ibuprofin. The Guy Who Beats Up Alan In one recurring gag, Kalter makes a statement on a particular topic, only to have a large man appear from nowhere and object to Kalter's comments.
Germolene cream contains the active ingredient chlorhexidine, which can rarely induce allergic reactions. [7] Symptoms of a minor allergic reaction to Germolene cream include itching , redness ( erythema ), dermatitis , eczema, rash , hives (urticaria), skin irritation , and blisters on the skin.
Neomycin is an aminoglycoside antibiotic that displays bactericidal activity against Gram-negative aerobic bacilli and some anaerobic bacilli where resistance has not yet arisen. It is generally not effective against Gram-positive bacilli and anaerobic Gram-negative bacilli. Neomycin comes in oral and topical formulations, including creams ...
Due to concerns of developing resistance, use for greater than ten days is not recommended. [7] It is used as a cream or ointment applied to the skin. [6] Common side effects include itchiness and rash at the site of application, headache, and nausea. [6] Long term use may result in increased growth of fungi. [6] Use during pregnancy and ...
Though Polysporin is marketed in the US, it holds a much smaller market share than in Canada and acts as a substitute to Johnson & Johnson's Neosporin for those allergic to the antibiotic neomycin. However, allergy to bacitracin/polymyxin B has also been reported. [2] There is also an ophthalmological ointment, eye and ear drops.
Polymyxin antibiotics are relatively neurotoxic and nephrotoxic, so are usually used only as a last resort if modern antibiotics are ineffective or are contraindicated. . Typical uses are for infections caused by strains of multiple drug-resistant Pseudomonas aeruginosa or carbapenemase-producing Enterobacteri