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Permethrin is a medication and an insecticide. [4] [5] As a medication, it is used to treat scabies and lice. [6] It is applied to the skin as a cream or lotion. [4] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them. [5] [7] Side effects include rash and irritation where it is applied. [6]
Pyrethrum rapidly knocks down flying insects but has negligible persistence — which is good for the environment but gives poor efficacy when applied in the field. Pyrethroids are essentially chemically stabilized forms of natural pyrethrum and belong to IRAC MoA group 3 (they interfere with sodium transport in insect nerve cells).
Bifenthrin has been approved for use against the Rasberry crazy ant in the Houston, Texas, area, under a special "crisis exemption" from the Texas Department of Agriculture and the EPA. The chemical is only approved for use in Texas counties experiencing "confirmed infestations" of the newly imported, invasive ant species. [17]
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Insects subject to exposure become paralyzed (nervous system effect) before dying. Allethrins are toxic to cats [ 5 ] because they either do not produce, or produce less of certain isoforms of glucuronosyltransferase , which serve in hepatic detoxifying metabolism pathways.
Permethrin can be applied as a spray. The effects are not limited to mites: lice, cockroaches, fleas, mosquitos, and other insects will be affected. Ivermectin can be prescribed by a medical doctor to rid humans of mite and lice infestations, and agricultural formulations are available for infested birds and rodents. Antibiotic miticides
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