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Estradiol/levonorgestrel (E2/LNG), sold under brand name Climara Pro, is a combination of estradiol (E2) and levonorgestrel (LNG) which is used in menopausal hormone therapy. [ 1 ] [ 2 ] [ 3 ] It is a 22-cm 2 transdermal patch containing 4.4 mg estradiol and 1.39 mg levonorgestrel and delivers 45 μg/day estradiol and 15 μg/day levonorgestrel.
An estrogen patch, or oestrogen patch, is a transdermal delivery system for estrogens such as estradiol and ethinylestradiol which can be used in menopausal hormone therapy, feminizing hormone therapy for transgender women, hormonal birth control, and other uses. [1] Transdermal preparations of estrogen are metabolized differently than oral ...
Estradiol and progesterone (Bijuva) – 0.5 mg / 100 mg; 1 mg / 100 mg [3] Transdermal patches. Estradiol and levonorgestrel (Climara Pro) ...
Climara [c] Estrogen: TD patch: 25–400 μg/day Divigel [c] Estrogen: TD gel: 0.5–5 mg/day Various: Estrogen: SC implant: 50–200 mg every 6–24 mos Estradiol valerate: Progynova: Estrogen: Oral: 2–10 mg/day Progynova: Estrogen: Sublingual: 1–8 mg/day Delestrogen [c] Estrogen: IM, SC: 2–10 mg/wk or 5–20 mg every 2 wks Estradiol ...
The patch-free interval must not be longer than seven days; otherwise, additional non-hormonal contraceptive methods must be used, such as condoms. [6] Transdermal patches must always be applied on the same day of the week to the buttock, abdomen (belly), upper arm or upper back. [ 6 ]
In general, Climara-type estradiol transdermal patches have an approximate 1:1 ratio of estradiol delivered in μg/day relative to circulating estradiol concentration in pg/mL. [205] In other words, a 100 μg/day Climara estradiol patch may be expected to produce circulating estradiol levels of around 100 pg/mL. [205]
120-150 μg of norelgestromin and 20-35 μg ethinyl estradiol daily [20] [21] [22] New patch used once a week, after 3 weeks patch is not worn to allow for withdrawal bleeding [19] Combined contraceptive vaginal ring [7] 120-150 μg etonogestrel and 13-15 μg ethinyl estradiol daily [20] [23] [24]
A contraceptive patch, also known as "the patch", is a transdermal patch applied to the skin that releases synthetic oestrogen and progestogen hormones to prevent pregnancy. They have been shown to be as effective as the combined oral contraceptive pill with perfect use, and the patch may be more effective in typical use.
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