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Phenylalanine is a large, neutral amino acid (LNAA). LNAAs compete for transport across the blood–brain barrier (BBB) via the large neutral amino acid transporter (LNAAT). If phenylalanine is in excess in the blood, it will saturate the transporter. Excessive levels of phenylalanine tend to decrease the levels of other LNAAs in the brain.
A non-food source of phenylalanine is the artificial sweetener aspartame. This compound is metabolized by the body into several chemical byproducts including phenylalanine. The breakdown problems phenylketonurics have with the buildup of phenylalanine in the body also occurs with the ingestion of aspartame, although to a lesser degree.
Because aspartame contains phenylalanine, foods containing aspartame sold in the US must state: "Phenylketonurics: Contains Phenylalanine" on product labels. [9] In the UK, foods that contain aspartame are required by the Food Standards Agency to list the substance as an ingredient, with the warning "Contains a source of phenylalanine ...
In fact, in many respects, the two foods are largely equivalent. Both gnocchi and pasta are rich in energizing carbohydrates but low on fiber and protein. Generally, gnocchi contains fewer ...
Advocates say drinks employing these sweeteners have a more natural sugar-like taste than those made just with aspartame, and do not have a strong aftertaste. The newer aspartame-free drinks can also be safely consumed by phenylketonurics, because they do not contain phenylalanine. Critics say the taste is not better, merely different, or note ...
Food poisoning, also known as foodborne illness, is a common sickness caused by swallowing food or liquids that contain harmful bacteria, viruses or parasites, and sometimes even chemicals.
The artificial sweetener aspartame has been the subject of several controversies since its initial approval by the U.S. Food and Drug Administration (FDA) in 1974. The FDA approval of aspartame was highly contested, beginning with suspicions of its involvement in brain cancer, [1] alleging that the quality of the initial research supporting its safety was inadequate and flawed, and that ...
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