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The study, "Shorter and Longer Antibiotic Durations for Respiratory Infections: To Fight Antimicrobial Resistance—A Retrospective Cross-Sectional Study in a Secondary Care Setting in the UK," highlights the urgency of reevaluating antibiotic treatment durations amidst the global challenge of antimicrobial resistance (AMR).
Antimicrobial resistance truly is one of the leading public health threats of our time,” said Emily Wheeler, director of infectious disease policy at the Biotechnology Innovation Organization ...
More broadly, the appearance of a new drug-resistant bacteria is a troubling development in the fight against “superbugs,” or pathogens resistant to most available antibiotics.
Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. [1] The term is used in the context of resistance that pathogens or cancers have "acquired", that is, resistance has evolved.
"The Global Leaders Group on Antimicrobial Resistance collaborates globally with governments, agencies, civil society and the private sector through a One Health approach to advise on and advocate for prioritized political actions for the mitigation of drug resistant infections through responsible and sustainable access to and use of antimicrobials."
Current BSAC activities include: Publishes the Journal of Antimicrobial Chemotherapy [5] and its sister publication, JAC-AMR. [6]Provides accreditation to hospitals as part of its Global Antimicrobial Stewardship Scheme (GAMSAS), [7] a programme of work that was used as a case study in the Government of the United Kingdom's National Action Plan on antimicrobial resistance, ‘Confronting ...
Resistance can then spread to other microbes and to other host organisms. Antimicrobial agents can also have direct toxic effects on people and animals, including damage to kidneys, endocrine glands, liver, teeth and bones. Antimicrobial therapy is justified when the benefits outweigh these risks.
Antimicrobial resistance is genetically based; resistance is mediated by the acquisition of extrachromosomal genetic elements containing genes that confer resistance to certain antibiotics. Examples of such elements include plasmids , transposable genetic elements , and genomic islands , which can be transferred between bacteria through ...