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Drugs can have various types of impact on the male body, side effects of medications may affect male fertility, spermatogenesis, and sexual function. Drugs can affect sperm parameters by inhibiting normal exocrine functions of the testes which can lead to a decrease in production of sperm, or by creating hormone imbalances. [4]
In medicine, hyperspermia is a condition in which a male has an abnormally large amount of semen or ejaculate volume [1] and is generally defined when the ejaculate is above 6 mL. [2] It is the opposite of hypospermia , which is defined as a semen volume of less than 1.5 mL.
A single semen sample is not determining for disease diagnosis, so two different samples have to be analyzed with an interval between them of seven days to three months, as sperm production is a cyclic process. It is prudent to ask about possible sample loss, as that could mask true results of spermiogram.
Many antibiotics, e.g., penicillin and tetracycline, suppress sperm production. [10] In addition, in vitro studies have observed altered sperm function by the following medications: Many psychoactive drugs, including many antidepressants, many antiepileptics (e.g., lithium), and propranolol [8] Opioid analgesics [8] Calcium channel blockers [8]
Reducing the frequency of sex and masturbation helps increase semen volume. Sexually transmitted diseases also affect the production of semen. Men who are infected [18] with the human immunodeficiency virus (HIV) produce lower semen volume. The volume of semen may also be increased, a condition known as hyperspermia. A volume greater than 6mL ...
A 1992 World Health Organization report described normal human semen as having a volume of 2 mL or greater, pH of 7.2 to 8.0, sperm concentration of 20×10 6 spermatozoa/mL or more, sperm count of 40×10 6 spermatozoa per ejaculate or more, and motility of 50% or more with forward progression (categories a and b) of 25% or more with rapid ...
Mesterolone, sold under the brand name Proviron among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels. [2] [3] It has also been used to treat male infertility, although this use is controversial. [2] [4] [5] It is taken by mouth. [2]
A study conducted by Selman and El-Danasouri in 2006 proved that using long-term gonadotropin therapy on infertile men can improve sperm production quantitatively and increase sperm population in some patients and can in turn provide a successful in-vitro fertilization treatment.
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