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Varenicline, sold under the brand names Chantix and Champix among others, is a medication used for smoking cessation [5] [7] and for the treatment of dry eye syndrome. [ 6 ] [ 8 ] It is a nicotinic acetylcholine receptor partial agonist .
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Chantix — Two parodies for the prescription medication used to treat nicotine addiction and its advertising that uses "real people [with] real stories": The first, from 2012, lists mental side effects that are worse than nicotine addiction itself, which user Kristen Wiig slowly discovers she has, much to husband Bill Hader's consternation (e ...
The first border between Wales and England was zonal, apart from around the River Wye, which was the first accepted boundary. [92] Offa's Dyke was supposed to form an early distinct line but this was thwarted by Gruffudd ap Llewellyn, who reclaimed swathes of land beyond the dyke. [ 92 ]
England, as part of the UK, joined the European Economic Community in 1973, which became the European Union in 1993. The UK left the EU in 2020. There is a movement in England to create a devolved English Parliament. This would give England a local Parliament like those already functioning for Scotland, Northern Ireland and Wales.
England is a country that is part of the United Kingdom. [7] It is located on the island of Great Britain, of which it covers about 62%, and more than 100 smaller adjacent islands.