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Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by an abnormally large increase in heart rate upon sitting up or standing. [1] POTS is a disorder of the autonomic nervous system that can lead to a variety of symptoms, [10] including lightheadedness, brain fog, blurred vision, weakness, fatigue, headaches, heart palpitations, exercise intolerance, nausea ...
A tilt table test (TTT), occasionally called upright tilt testing (UTT), is a medical procedure often used to diagnose dysautonomia or syncope. Patients with symptoms of dizziness or lightheadedness, with or without a loss of consciousness ( fainting ), suspected to be associated with a drop in blood pressure or positional tachycardia are good ...
Neuromelanin is an autoxidation byproduct of catecholamines, and it has been suggested that catecholaminergic neurons surrounded by a low density of glutathione peroxidase cells are more susceptible to degeneration in Parkinson's disease than those protected against oxidative stress.
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The results are only meaningful if performed in the correct order (starting with supine position). [ 2 ] [ 3 ] [ 4 ] Used to identify orthostatic hypotension , [ 5 ] orthostatic vital signs are commonly taken in triage medicine when a patient presents with vomiting , diarrhea or abdominal pain ; with fever ; with bleeding; or with syncope ...
Orthostatic intolerance occurs in humans because standing upright is a fundamental stressor, so requires rapid and effective circulatory and neurologic compensations to maintain blood pressure, cerebral blood flow, and consciousness. When a human stands, about 750 ml of thoracic blood are abruptly translocated downward.
Catecholamines are produced mainly by the chromaffin cells of the adrenal medulla and the postganglionic fibers of the sympathetic nervous system. Dopamine, which acts as a neurotransmitter in the central nervous system, is largely produced in neuronal cell bodies in two areas of the brainstem: the ventral tegmental area and the substantia nigra, the latter of which contains neuromelanin ...
Catecholaminergic means "related to catecholamines". The catecholamine neurotransmitters include dopamine , epinephrine (adrenaline), and norepinephrine (noradrenaline). A catecholaminergic agent (or drug ) is a chemical which functions to directly modulate the catecholamine systems in the body or brain.