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Metals have been used in treatments since ancient times. The Ebers Papyrus from 1500BC is the first written account of the use of metals for treatment and describes the use of Copper to reduce inflammation and the use of iron to treat anemia. Sodium vanadate has been used since the early 20th century to treat rheumatoid arthritis.
Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy: Molecular Mechanisms and Clinical Applications. Humana Press. ISBN 978-1-60327-458-6. Clarke MJ, Sadler PJ (1999). Metallopharmaceuticals: Diagnosis and therapy. Springer. ISBN 978-3-540-65308-0. Clarke MJ, Sadler PJ (1999). Metallopharmaceuticals I: DNA Interactions. Springer.
Metal ions and metallic compounds are often used in medical treatments and diagnoses. [18] Compounds containing metal ions can be used as medicine, such as lithium compounds and auranofin . [ 19 ] [ 20 ] Metal compounds and ions can also produce harmful effects on the body due to the toxicity of several types of metals. [ 18 ]
Bioorganometallic chemistry is the study of biologically active molecules that contain carbon directly bonded to metals or metalloids. The importance of main-group and transition-metal centers has long been recognized as important to the function of enzymes and other biomolecules.
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use.
Organoboron chemistry is mainly of commercial value in the pharmaceutical industry. Triethylborane was used to ignite the JP-7 fuel of the Pratt & Whitney J58 variable cycle engines powering the Lockheed SR-71 Blackbird. Organoboron compounds have long been discussed for use as boron delivery agents in neutron capture therapy of cancer. [51]
A steel bottle containing MgCp 2 (magnesium bis-cyclopentadienyl), which, like several other organometallic compounds, is pyrophoric in air.. Organometallic compounds are distinguished by the prefix "organo-" (e.g., organopalladium compounds), and include all compounds which contain a bond between a metal atom and a carbon atom of an organyl group. [2]
The pigment is used in paints, it became prominent in 19th-century aizuri-e (藍摺り絵) Japanese woodblock prints, and it is the traditional "blue" in technical blueprints. In medicine, orally administered Prussian blue is used as an antidote for certain kinds of heavy metal poisoning, e.g., by thallium(I) and radioactive isotopes of caesium.