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Metal complexes can be used either for radioisotope imaging (from their emitted radiation) or as contrast agents, for example, in magnetic resonance imaging (MRI). Such imaging can be enhanced by manipulation of the ligands in a complex to create specificity so that the complex will be taken up by a certain cell or organ type.
A metallopharmaceutical is a drug that contains a metal as an active ingredient. [1] [2] Most commonly metallopharmaceuticals are used as anticancer or antimicrobial agents. The efficiency of metallopharmaceuticals is crucially dependent on the respective trace metal binding forms. [3] Examples of metallopharmaceuticals include:
This list of pharmaceutical compound number prefixes provides codes used by individual pharmaceutical companies when naming their pharmaceutical drug candidates. . Pharmaceutical companies generally produce large numbers of compounds in the research phase for which it is impractical to use often long and cumbersome systematic chemical names, and for which the effort to generate nonproprietary ...
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use.
The Hierarchy of Occupational Exposure Limits, of which occupational exposure banding is a member. Occupational exposure banding, also known as hazard banding, is a process intended to quickly and accurately assign chemicals into specific categories (bands), each corresponding to a range of exposure concentrations designed to protect worker health.
The manager must also be acutely aware of safety standards in the handling and storing of radioactive, volatile, flammable and unstable compounds. Often, in large pharmaceutical companies, the chemical and biological compounds contained in compound libraries can number in the millions, making compound management and compound control important ...
Thallium(III) compounds resemble the corresponding aluminium(III) compounds. They are moderately strong oxidizing agents and are usually unstable, as illustrated by the positive reduction potential for the Tl 3+ /Tl couple. Some mixed-valence compounds are also known, such as Tl 4 O 3 and TlCl 2, which contain both thallium(I) and thallium(III).
Pharmaceutical companies usually have a number of compounds in their pipelines at any given time. The drug pipeline is an important indicator of the value and future prospects of a company . Usually the more compounds in the pipeline, and the more advanced stage that these are in the better.