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The epidemiology of hepatitis D occurs worldwide. [1] Although the figures are disputed, a recent systematic review suggests that up to 60 million individuals could be infected. [ 2 ] The major victims are the carriers of the hepatitis B surface antigen ( HBsAg ), who become superinfected by the HDV, and intravenous drug users who are the group ...
The prenylation inhibitor lonafarnib prevents hepatitis D viral particle assembly by inhibiting the farnesylation of the L-HDAg. [53] REP2139-Ca is a nucleic acid polymer that prevents the release of hepatitis B surface antigen (which is required for assembly of hepatitis D viral particles). [54]
The National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), formerly the National Center for HIV, STD, and TB Prevention (NCHSTP) is a part of the Centers for Disease Control and Prevention and is responsible for public health surveillance, prevention research, and programs to prevent and control human immunodeficiency virus (HIV) infection and acquired ...
Clinical Infectious Diseases is a peer-reviewed medical journal published by Oxford University Press covering research on the pathogenesis, clinical investigation, medical microbiology, diagnosis, immune mechanisms, and treatment of diseases caused by infectious agents.
Hepatitis D is caused by the hepatitis D virus (HDV), or hepatitis delta virus; it belongs to the genus Deltavirus. HDV is similar to a satellite virus as it can only propagate in the presence of the hepatitis B virus, depending on the helper function of HBV for its replication and expression. It has no independent life cycle, but can survive ...
Hepatitis D is a defective virus that requires hepatitis B to replicate and is only found with hepatitis B co-infection. [17] In adults, hepatitis B infection is most commonly self-limiting, with less than 5% progressing to chronic state, and 20 to 30% of those chronically infected developing cirrhosis or liver cancer. [ 31 ]
Research topics include: antigenic shift; epidemiological networks; evolution and spread of resistance; immuno-epidemiology; intra-host dynamics; Pandemic; pathogen population genetics; persistence of pathogens within hosts; phylodynamics; role and identification of infection reservoirs; role of host genetic factors; spatial epidemiology
An epidemic curve, also known as an epi curve or epidemiological curve, is a statistical chart used in epidemiology to visualise the onset of a disease outbreak. It can help with the identification of the mode of transmission of the disease. It can also show the disease's magnitude, whether cases are clustered or if there are individual case ...