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Acetylcholinesterase inhibitors are one of two types of cholinesterase inhibitors; the other being butyryl-cholinesterase inhibitors. [2] Acetylcholinesterase is the primary member of the cholinesterase enzyme family. [3] Acetylcholinesterase inhibitors are classified as reversible, irreversible, or quasi-irreversible (also called pseudo ...
Pages in category "Acetylcholinesterase inhibitors" The following 200 pages are in this category, out of approximately 218 total. This list may not reflect recent changes .
Paraoxon and rivastigmine are both acetylcholinesterase inhibitors and butyrylcholinesterase inhibitors. [14] [11] [7]In 2015, the United States Food and Drug Administration's Adverse Event Reporting System database compared rivastigmine to the other ChEI drugs donepezil and galantamine found that rivastigmine was associated with a higher frequency of reports of death as an adverse event.
Reversible acetylcholinesterase inhibitor agents such as physostigmine can be used as an antidote in life-threatening cases. Wider use is discouraged due to the significant side effects related to cholinergic excess including seizures, muscle weakness, bradycardia, bronchoconstriction, lacrimation, salivation, bronchorrhea, vomiting, and diarrhea.
More severe side effects include low blood pressure, weakness, and allergic reactions. [3] It is unclear if use in pregnancy is safe for the fetus. [3] Pyridostigmine is an acetylcholinesterase inhibitor in the cholinergic family of medications. [3] It works by blocking the action of acetylcholinesterase and therefore increases the levels of ...
Acetylcholinesterase inhibitor. Donepezil: Donepezil may exhibit cardiac issues such as hypertension, cardiac arrhythmia, atrioventricular block, and bradycardia due to its vagotonia properties. [2] Common gastrointestinal side effects such as nausea, diarrhea, and vomiting are also associated with donepezil and other acetylcholinesterase ...
Physostigmine, an acetylcholinesterase inhibitor, can be used to treat glaucoma and delayed gastric emptying.Because it enhances the transmission of acetylcholine signals in the brain and can cross the blood–brain barrier, physostigmine salicylate is used to treat anticholinergic poisoning (that is, poisoning by substances that interfere with the transmission of acetylcholine signaling, such ...
Cholinergic blocking drugs are a group of drugs that block the action of acetylcholine (ACh), a neurotransmitter, in synapses of the cholinergic nervous system. [1] They block acetylcholine from binding to cholinergic receptors, namely the nicotinic and muscarinic receptors.
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261