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  2. Allele frequency - Wikipedia

    en.wikipedia.org/wiki/Allele_frequency

    Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. [1] Specifically, it is the fraction of all chromosomes in the population that carry that allele over the total population or sample size.

  3. Allele frequency spectrum - Wikipedia

    en.wikipedia.org/wiki/Allele_frequency_spectrum

    The allele frequency spectrum can be written as the vector = (,,,,), where is the number of observed sites with derived allele frequency .In this example, the observed allele frequency spectrum is (,,,,), due to four instances of a single observed derived allele at a particular SNP loci, two instances of two derived alleles, and so on.

  4. Genotype frequency - Wikipedia

    en.wikipedia.org/wiki/Genotype_frequency

    The Hardy–Weinberg law describes the relationship between allele and genotype frequencies when a population is not evolving. Let's examine the Hardy–Weinberg equation using the population of four-o'clock plants that we considered above: if the allele A frequency is denoted by the symbol p and the allele a frequency denoted by q, then p+q=1.

  5. Minor allele frequency - Wikipedia

    en.wikipedia.org/wiki/Minor_allele_frequency

    Minor allele frequency (MAF) is the frequency at which the second most common allele occurs in a given population. They play a surprising role in heritability since MAF variants which occur only once, known as "singletons", drive an enormous amount of selection.

  6. Allele - Wikipedia

    en.wikipedia.org/wiki/Allele

    where p is the frequency of one allele and q is the frequency of the alternative allele, which necessarily sum to unity. Then, p 2 is the fraction of the population homozygous for the first allele, 2pq is the fraction of heterozygotes, and q 2 is the fraction homozygous for the alternative allele.

  7. Mutation rate - Wikipedia

    en.wikipedia.org/wiki/Mutation_rate

    Different genetic variants within a species are referred to as alleles, therefore a new mutation can create a new allele. In population genetics, each allele is characterized by a selection coefficient, which measures the expected change in an allele's frequency over time. The selection coefficient can either be negative, corresponding to an ...

  8. Fixation (population genetics) - Wikipedia

    en.wikipedia.org/wiki/Fixation_(population_genetics)

    In the process of substitution, a previously non-existent allele arises by mutation and undergoes fixation by spreading through the population by random genetic drift or positive selection. Once the frequency of the allele is at 100%, i.e. being the only gene variant present in any member, it is said to be "fixed" in the population. [1]

  9. Population genetics - Wikipedia

    en.wikipedia.org/wiki/Population_genetics

    allele frequency – the frequency or proportion of a particular allele of a gene within a population; s is the selection coefficient and h is the dominance ...