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Betahistine was once believed to have some positive effects in the treatment of Ménière's disease and vertigo, [3] but more recent evidence casts doubt on its efficacy. [4] [5] Studies of the use of betahistine have shown a reduction in symptoms of vertigo and, to a lesser extent, tinnitus, but conclusive evidence is lacking at present.
Betahistine at high doses (such as 144 mg/day) can yield similar vertigo control as intratympanic dexamethasone. [16] [17] Antivirals have been proven effective for those who suspect a viral cause for their cochlear Hydrops. [18] For some, surgery may be effective, such as an endolymphatic sac decompression. Surgery is often reserved for cases ...
This is followed by gently bringing the head back to the starting position. The examiner then quickly rotates the head 90° to the right side and checks again for vertigo and nystagmus. [24] In this roll test, the person may experience vertigo and nystagmus on both sides, but rotating toward the affected side will trigger a more intense vertigo.
A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes.. H 1 agonists promote wakefulness. [1]H 2: Betazole and Impromidine are examples of agonists used in diagnostics to increase histamine.
An H 3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H 3 receptors.. Unlike the H 1 and H 2 receptors which have primarily peripheral actions, but cause sedation if they are blocked in the brain, H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of ...
Treatment with drugs is neither effective nor necessary. The effect of glucocorticoids has been studied, but they have not been found to significantly affect long-term outcome. [26] Symptomatic treatment with antihistaminics such as cinnarizine, however, can be used to suppress the symptoms of vestibular neuritis while it spontaneously ...
Heavy-headedness can be caused by inner ear disturbance, motion sickness and medication effects. Sometimes it can be caused by an underlying health condition, such as poor circulation, infections or injuries. [4] Panic attacks can cause heavy-headedness as well. Medical conditions like anxiety causes heavy-headedness too. [5]
Flunarizine is a selective calcium antagonist with moderate other actions including antihistamine, serotonin receptor blocking and dopamine D 2 blocking activity. Compared to other calcium channel blockers such as dihydropyridine derivatives, verapamil and diltiazem, flunarizine has low affinity to voltage-dependent calcium channels.
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