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Chelation (/ k iː ˈ l eɪ ʃ ən /) is a type of bonding of ions and their molecules to metal ions. It involves the formation or presence of two or more separate coordinate bonds between a polydentate (multiple bonded) ligand and a single central metal atom.
DOTA is derived from the macrocycle known as cyclen.The four secondary amine groups are modified by replacement of the N-H centers with N-CH 2 CO 2 H groups. The resulting aminopolycarboxylic acid, upon ionization of the carboxylic acid groups, is a high affinity chelating agent for di- and trivalent cations.
DOTA (chelator) derivatives (6 P) S. Sequestrants (1 P) Siderophores (23 P) Pages in category "Chelating agents" The following 164 pages are in this category, out of ...
Meaning SI unit of measure alpha: alpha particle: angular acceleration: radian per second squared (rad/s 2) fine-structure constant: unitless beta: velocity in terms of the speed of light c: unitless beta particle: gamma: Lorentz factor: unitless photon: gamma ray: shear strain: radian
TPEN (N,N,N ′,N ′-tetrakis(2-pyridinylmethyl)-1,2-ethanediamine [1]) is an intracellular membrane-permeable ion chelator. [2] TPEN has a high affinity for many transition metals and should not be considered specific or selective for a particular ion. Chelators can be used in chelation therapy to remove toxic metals in the body. TPEN is a ...
DOTAM (also known as TCMC) is an organic compound used as a chelator much like its carboxylic acid analog DOTA. A derivative with a reactive linking group of para-isothiocyanatobenzyl attached to the cyclen ring is also of interest as a bifunctional chelator (BFC).
EDDHA or ethylenediamine-N,N ′-bis(2-hydroxyphenylacetic acid) is a chelating agent.Like EDTA, it binds metal ions as a hexadentate ligand, using two amines, two phenolate centers, and two carboxylates as the six binding sites.
Also acid ionization constant or acidity constant. A quantitative measure of the strength of an acid in solution expressed as an equilibrium constant for a chemical dissociation reaction in the context of acid-base reactions. It is often given as its base-10 cologarithm, p K a. acid–base extraction A chemical reaction in which chemical species are separated from other acids and bases. acid ...