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  2. List of side effects of tramadol - Wikipedia

    en.wikipedia.org/wiki/List_of_side_effects_of...

    This page was last edited on 19 October 2024, at 12:13 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.

  3. Tramadol - Wikipedia

    en.wikipedia.org/wiki/Tramadol

    Tramadol was patented in 1972 and launched under the name "Tramal" in 1977 by the West German pharmaceutical company Grünenthal GmbH. [16] [20] In the mid-1990s, it was approved in the United Kingdom and the United States. [16] It is available as a generic medication and marketed under many brand names worldwide.

  4. N,O-Didesmethyltramadol - Wikipedia

    en.wikipedia.org/wiki/N,O-didesmethyltramadol

    N,O-Didesmethyltramadol (tramadol metabolite M5) is an opioid derivative which is one of two active metabolites of the opioid analgesic medication tramadol.It is many times less potent than the other active metabolite O-Desmethyltramadol but is still more potent as a mu opioid receptor agonist than tramadol itself, unlike the other metabolites N-desmethyltramadol, N,N-didesmethyltramadol, and ...

  5. It’s not just border cities that have seen deaths and overdoses from fentanyl-tainted pills bought in Mexican pharmacies. The 2019 case that wound up on the DEA’s radar stemmed from a purchase ...

  6. Tramadol/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Tramadol/paracetamol

    Tramadol/paracetamol, also known as tramadol/acetaminophen and sold under the brand name Ultracet among others, is a fixed-dose combination medication used for the treatment of moderate to severe pain. [3] [4] It contains tramadol, as the hydrochloride, an analgesic; and paracetamol an analgesic. [3] [4] It is taken by mouth. [3] [4]

  7. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.

  8. Martindale: The Complete Drug Reference - Wikipedia

    en.wikipedia.org/wiki/Martindale:_The_complete...

    Martindale: The Complete Drug Reference is a reference book published by Pharmaceutical Press listing some 6,000 drugs and medicines used throughout the world, including details of over 125,000 proprietary preparations.

  9. Modified-release dosage - Wikipedia

    en.wikipedia.org/wiki/Modified-release_dosage

    Modified-release dosage and its variants are mechanisms used in tablets (pills) and capsules to dissolve a drug over time in order to be released more slowly and steadily into the bloodstream, while having the advantage of being taken at less frequent intervals than immediate-release (IR) formulations of the same drug.

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