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In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. [3] A trough level is contrasted with a "peak level" (C max), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It is ...
Peak-to-trough ratio in pharmacokinetics is the ratio of peak (C max) and trough (C min) levels of a drug over its dosing interval (τ) at steady state.. Peak-to-trough ratio (PTR), also known as peak-to-trough variation or peak-to-trough fluctuation, is a parameter in pharmacokinetics which is defined as the ratio of C max (peak) concentration and C min (trough) concentration over a dosing ...
Mark Vanco (born October 13, 1968) is an American designer and artist, associated with the cyberpunk aesthetic. He is the creator of Rotor, a clothing company. He is the creator of Rotor, a clothing company.
A parabolic trough collector (PTC) is a type of solar thermal collector that is straight in one dimension and curved as a parabola in the other two, lined with a polished metal mirror. The sunlight which enters the mirror parallel to its plane of symmetry is focused along the focal line , where objects are positioned that are intended to be heated.
For forty years the arithmometer was the only type of mechanical calculator available for sale until the industrial production of the more successful Odhner Arithmometer in 1890. [8] The comptometer, introduced in 1887, was the first machine to use a keyboard that consisted of columns of nine keys (from 1 to 9) for each digit.
The predicted no-effect concentration (PNEC) is the concentration of a chemical which marks the limit at which below no adverse effects of exposure in an ecosystem are measured. PNEC values are intended to be conservative and predict the concentration at which a chemical will likely have no toxic effect.
A partially disassembled Curta calculator, showing the digit slides and the stepped drum behind them Curta Type I calculator, top view Curta Type I calculator, bottom view. The Curta is a hand-held mechanical calculator designed by Curt Herzstark. [1] It is known for its extremely compact design: a small cylinder that fits in the palm of the hand.
The Electronic Delay Storage Automatic Calculator (EDSAC) was an early British computer. [1] Inspired by John von Neumann 's seminal First Draft of a Report on the EDVAC , the machine was constructed by Maurice Wilkes and his team at the University of Cambridge Mathematical Laboratory in England.