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Mucociliary clearance has a major role in pulmonary hygiene. MCC effectiveness relies on the correct properties of the airway surface liquid produced, both of the periciliary sol layer and the overlying mucus gel layer, and of the number and quality of the cilia present in the lining of the airways. [3] An important factor is the rate of mucin ...
Mucokinetics: increase mucociliary transport (clearance) and transportability of mucus by cough [2] Mucoregulators: suppress underlying mechanisms of mucus hypersecretion [2] Alternatively, attacking the affinity between secretions and the biological surfaces is another avenue, which is used by abhesives and surfactants. [citation needed]
The ability of various influenza strains to show species-selectivity is largely due to variation in the hemagglutinin genes. Genetic mutations in the hemagglutinin gene that cause single amino acid substitutions can significantly alter the ability of viral hemagglutinin proteins to bind to receptors on the surface of host cells.
The cells in the respiratory epithelium are of five main types: a) ciliated cells, b) goblet cells, c) brush cells, d) airway basal cells, and e) small granule cells (NDES) [6] Goblet cells become increasingly fewer further down the respiratory tree until they are absent in the terminal bronchioles; club cells take over their role to some extent here. [7]
Dr Terrence Tumpey examines a reconstructed version of the Spanish flu virus at the CDC. An effort to recreate the Spanish flu strain (a strain of influenza A subtype H1N1) was a collaboration among the Armed Forces Institute of Pathology, the USDA ARS Southeast Poultry Research Laboratory, and Mount Sinai School of Medicine in New York
Spanish flu or Spanish influenza, also known as purulent bronchitis, may refer to: . the 1918 flu pandemic where 500 million people worldwide were infected with H1N1 influenza A virus between 1918 and 1920, killing from 20 to 100 million people
Airway basal cells are found deep in the respiratory epithelium, attached to, and lining the basement membrane. [1]Basal cells are the stem cells or progenitors of the airway epithelium and can differentiate to replenish all of the epithelial cells including the ciliated cells, and secretory goblet cells.
Pages for logged out editors learn more. Contributions; Talk; Spanish Influenza