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In the 1960s and 1970s, John Vane and others discovered the basic mechanism of aspirin's effects, [3]: 226–231 while clinical trials and other studies from the 1960s to the 1980s established aspirin's efficacy as an anti-clotting agent that reduces the risk of clotting diseases.
Heinrich Dreser, 1897. Heinrich Dreser (1 October 1860 – 21 December 1924) was a German chemist responsible for the aspirin and heroin projects at Bayer AG.He was also a key figure in creating the widely used modern drug codeine.
Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [10] For pain or fever, effects typically begin within 30 minutes. [10] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [10] One common adverse effect is an upset ...
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Seeds likely used for herbalism have been found in archaeological sites of Bronze Age China dating from the Shang dynasty [10] (c. 1600 BCE–c. 1046 BCE). Over a hundred of the 224 drugs mentioned in the Huangdi Neijing – an early Chinese medical text – are herbs. [ 11 ]
Felix Hoffmann (21 January 1868 – 8 February 1946) was a German chemist notable for re-synthesising diamorphine (independently from C.R. Alder Wright who synthesized it 23 years earlier), which was popularized under the Bayer trade name of "heroin".
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Salicylic acid is a phenolic phytohormone, and is found in plants with roles in plant growth and development, photosynthesis, transpiration, and ion uptake and transport. [53] Salicylic acid is involved in endogenous signaling, mediating plant defense against pathogens . [ 54 ]