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CA-125 was initially detected using the murine monoclonal antibody designated OC125. Robert Bast , Robert Knapp and their research team first isolated this monoclonal antibody in 1981. [ 28 ] The protein was named "cancer antigen 125" because OC125 was the 125th antibody produced against the ovarian cancer cell line that was being studied.
CA-125: Mainly ovarian cancer, [12] but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer. [13] Calcitonin: medullary thyroid carcinoma [14] Calretinin: mesothelioma, sex cord-gonadal stromal tumor, adrenocortical carcinoma, synovial sarcoma [8] Carcinoembryonic ...
CA-125 levels are not accurate in early stage ovarian cancer, as half of stage I ovarian cancer patients have a normal CA-125 level. [31] [29] CA-125 may also be elevated in benign (non-cancerous) conditions, including endometriosis, pregnancy, uterine fibroids, menstruation, ovarian cysts, systemic lupus erythematosus, liver disease ...
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
The results of this trial demonstrated a stable disease for 10/18 patients ( 56%) and had no immunogenic response. M5A-DOTA was coupled with 225-Ac , which is an alpa emitter, and an in vivo study was performed where cytokine therapy was combined with a-therapy. [30] The result of the study revealed the benefit of combining these two treamtents.
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Elevated 1,25(OH) 2 D (see calcitriol under Vitamin D) levels (e.g., sarcoidosis and other granulomatous diseases such as tuberculosis, berylliosis, histoplasmosis, Crohn's disease, and granulomatosis with polyangiitis) Idiopathic hypercalcaemia of infancy [23] Rebound hypercalcaemia after rhabdomyolysis
The Oakland Unified School District, California's 11th-largest public school district, said in a letter to families that it had tested over 1,000 faucets and fountains at 40 TK-12 schools to ...