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TOL-463 is an anti-infective medication which is under development for the treatment of bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC) (vaginal yeast infection). [ 3 ] [ 1 ] [ 4 ] [ 2 ] It is a boric acid -based vaginal anti-infective enhanced with ethylenediaminetetraacetic acid (EDTA) which was designed to have improved activity ...
Prasterone enanthate, also known as dehydroepiandrosterone enanthate (DHEA-E) and sold in combination with estradiol valerate under the brand name Gynodian Depot among others, is a weak androgen, estrogen, and neurosteroid medication which is used as a component of menopausal hormone therapy to treat menopausal symptoms in women.
It can also be caused by hot tubs, abrasion, tissue, tampons, or topical medications. Foreign body vaginitis (most common foreign bodies are retained tampons or condoms) may cause extremely malodorous vaginal discharges. Treatment consists of removal, for which ring forceps may be useful. Further treatment is generally not necessary.
Antiestrogen medications may also contribute to the development of atrophic vaginitis. These medications include danazol, nafarelin, and medroxyprogesterone. Additional risk factors include smokers, those who have not given birth naturally (through the vagina), and increased prolactin levels while lactation. [14]
Anaerobic vaginositis, non-specific vaginitis, vaginal bacteriosis, Gardnerella vaginitis [1] Vaginal squamous cell with normal vaginal flora versus bacterial vaginosis on Pap stain . Normal vaginal flora (left) is predominantly rod-shaped Lactobacilli whereas in bacterial vaginosis (right) there is an overgrowth of bacteria which can be of ...
Vaginal yeast infections are due to excessive growth of Candida. [1] These yeast are normally present in the vagina in small numbers. [1] Vaginal yeast infections are typically caused by the yeast species Candida albicans. Candida albicans is a common fungus often harbored in the mouth, digestive tract, or vagina without causing adverse ...
Vaginal miconazole 20 mg/g - Brazil. Oral treatment: (brand names Daktarin in UK, Fungimin Oral Gel in Bangladesh): [citation needed] In 2010, the US Food and Drug Administration approved Oravig (miconazole) buccal tablets for the local treatment of oropharyngeal candidiasis, more commonly known as thrush, in adults and children age 16 and ...
Vaginal weight had a 1.46x increase after a two-week treatment of 10 mg/kg/day of ospemifene. [10] The number of progesterone receptors was increased in the vaginal stroma and epithelium, which indicates that ospemifene has "estrogenic activity." [10] Two 12-week phase 3 clinical trials were performed for ospemifene. [14]
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