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The primary indication for endometrial ablation is abnormal uterine bleeding, including chronic heavy menstrual bleeding, in premenopausal patients. [6] Typically, these are patients for whom first-line medical therapy was unsuccessful or contraindicated. [1] In some cases, endometrial ablation is use to treat small uterine fibroids. [7]
A further surgical technique is endometrial ablation (destruction) by the use of applied heat (thermoablation). [58] The effectiveness of endometrial ablation is probably similar to that of LNG‐IUS but the evidence is uncertain if hysterectomy is better or worse than LNG-IUS for improving HMB. [21]
Illustration of uterine fibroids with examples of their possible locations. Uterine artery embolization (UAE, uterine fibroid embolization, or UFE) is a procedure in which an interventional radiologist uses a catheter to deliver small particles that block the blood supply to the uterine body.
Dilation (or dilatation) and curettage (D&C) refers to the dilation (widening or opening) of the cervix and surgical removal of sections and/or layers of the lining of the uterus and or contents of the uterus such as an unwanted fetus (early abortion before 13 weeks), remains of a non-viable fetus, retained placenta after birth or abortion as well as any abnormal tissue which may be in the ...
In 2001–2002, 11.4% of patients diagnosed with asthma and seen at an outpatient visit were prescribed oral corticosteroids as a long-term control therapy. [14] The National Asthma Education and Prevention Program (NAEPP) indicates systemic methylprednisolone in both short and long-term therapies to quickly control and to suppress persistent ...
Megestrol acetate was reported to be effective in the treatment of endometrial hyperplasia in the mid-1960s. [6] It first started to be studied as a treatment for endometrial cancer in 1967, with findings published in 1973. [6] [156] [157] Megestrol acetate was reportedly introduced for the treatment of endometrial cancer in the United States ...
Toxicological issues prevented long term use of clomifene and further drug development for other potential applications such as breast cancer treatment and prevention. [ 8 ] It was another ten years before tamoxifen was approved in December 1977, not as a contraceptive but as a hormonal treatment to treat and prevent breast cancer. [ 8 ]
Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins. [7] [8] In the past, EE was widely used for various indications such as the treatment of menopausal symptoms, gynecological disorders, and certain hormone-sensitive cancers.