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An early age of onset of muscle weakness and heart disease (onset in childhood or adolescence) Some learning problems or intellectual disability can be present; Muscle weakness can be severe and can affect endurance and the ability to walk; Heart disease (cardiomyopathy) can be severe and can lead to a need for medications.
Cardiomyopathy is a group of primary diseases of the heart muscle. [1] Early on there may be few or no symptoms. [1] As the disease worsens, shortness of breath, feeling tired, and swelling of the legs may occur, due to the onset of heart failure. [1]
[citation needed] Weakness of the peroneal muscles can result in toe walking, which can present in the first decade of life. [1] Facial, hand, and thigh muscles can be affected, although less often. [1] Calf hypertrophy can occur. [1] Involvement of the heart occurs in almost all cases, presenting as syncope in the second or third decades, or ...
True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular junction disorders, such as myasthenia gravis. Muscle weakness can also be caused by low levels of potassium and other electrolytes within muscle cells. It can be temporary or ...
Coronary arteries deliver oxygen-rich blood to the heart muscle. [5] Reduced blood flow to the heart associated with coronary ischemia can result in inadequate oxygen supply to the heart muscle. [6] When oxygen supply to the heart is unable to keep up with oxygen demand from the muscle, the result is the characteristic symptoms of coronary ...
This impairs the arteries from delivering adequate blood flow and oxygen to the heart muscle. [10] Together, these events can lead to congestive heart failure and decrease the heart's output of blood with each squeeze. [10] Takotsubo cardiomyopathy occurs worldwide. [11]
The causes are many and can be divided into conditions that have either true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular diseases, such as myasthenia gravis. Perceived muscle weakness occurs in ...
In early to middle age, bone density and muscle mass are closely related. As adults age, skeletal muscle mass or bone density may begin to decline. This decline can lead to frailty and both have been identified as contributors to disability. [18] Muscle weakness makes it difficult to perform everyday activities, like getting into a bathtub.
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