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Cardiomyopathy is a group of primary diseases of the heart muscle. [1] Early on there may be few or no symptoms. [1] As the disease worsens, shortness of breath, feeling tired, and swelling of the legs may occur, due to the onset of heart failure. [1]
[11] [12] Further, this adrenaline surge triggers the arteries to tighten, thereby raising blood pressure and placing more stress on the heart, and may lead to spasm of the coronary arteries that supply blood to the heart muscle. [10] This impairs the arteries from delivering adequate blood flow and oxygen to the heart muscle. [10]
Thiamine deficiency, in particular, is common in people with alcohol use disorder and can lead to a condition known as beriberi, which can damage the heart muscle. [4] Furthermore, chronic alcohol consumption can also lead to other cardiovascular risk factors, such as high blood pressure, high cholesterol levels, and obesity, which can ...
Coronary arteries deliver oxygen-rich blood to the heart muscle. [5] Reduced blood flow to the heart associated with coronary ischemia can result in inadequate oxygen supply to the heart muscle. [6] When oxygen supply to the heart is unable to keep up with oxygen demand from the muscle, the result is the characteristic symptoms of coronary ...
An early age of onset of muscle weakness and heart disease (onset in childhood or adolescence) Some learning problems or intellectual disability can be present; Muscle weakness can be severe and can affect endurance and the ability to walk; Heart disease (cardiomyopathy) can be severe and can lead to a need for medications.
[citation needed] Weakness of the peroneal muscles can result in toe walking, which can present in the first decade of life. [1] Facial, hand, and thigh muscles can be affected, although less often. [1] Calf hypertrophy can occur. [1] Involvement of the heart occurs in almost all cases, presenting as syncope in the second or third decades, or ...
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