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Isosorbide dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart. [1] It has been found to be particularly useful in heart failure due to systolic dysfunction together with hydralazine .
The combination of isosorbide dinitrate/hydralazine is the only vasodilator regimen, other than ACE inhibitors or angiotensin II receptor antagonists, with proven survival benefits. This combination appears to be particularly beneficial in CHF patients with an African American background, who respond less effectively to ACEI therapy.
[4] [12] [14] [17] [27] Therapeutic alternatives with similar clinical performance are listed for some medicines and they may be considered for national essential medicines lists. [17] [18] The 9th Essential Medicines List for Children was updated in July 2023. [23] [28] Note: An α indicates a medicine is on the complementary list. [4] [14] [17]
Isosorbide is a bicyclic ... 2,5-isosorbide dinitrate ... Phosphoric acid derivatives of isosorbide are explored as an environmentally friendly alternative to ...
Nicorandil is a vasodilator drug used to treat angina.. Angina is chest pain that results from episodes of transient myocardial ischemia.This can be caused by diseases such as atherosclerosis, coronary artery disease and aortic stenosis.
The nitrate esters isosorbide dinitrate (Isordil) and isosorbide mononitrate (Imdur, Ismo, Monoket, Mononitron) are converted in the body to nitric oxide, a potent natural vasodilator. In medicine, these esters are used as a medicine for angina pectoris (ischemic heart disease).
The new drug application claiming treatment of a single, self-identified racial group raised a storm of controversy. Some hailed the development of BiDil as a breakthrough for Black Americans (such groups included the congressional Black Caucus, the Association of Black Cardiologists, the National Medical Association, and the National Association for the Advancement of Colored People) and a ...
Vericiguat is a direct stimulator of soluble guanylate cyclase, an important enzyme in vascular smooth muscle cells. Specifically, vericiguat binds to the beta-subunit of the target site on the soluble guanylate cyclase enzyme. [11]
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261
The lowest prices on specific drugs - Family Circle