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As Parkinson's is a heterogeneous condition with multiple etiologies, prognostication can be difficult and prognoses can be highly variable. [220] [222] On average, life expectancy is reduced in those with Parkinson's, with younger age of onset resulting in greater life expectancy decreases. [223]
Accurate diagnosis of these Parkinson-plus syndromes is improved when precise diagnostic criteria are used. [2] Since diagnosis of individual Parkinson-plus syndromes is difficult, the prognosis is often poor. Proper diagnosis of these neurodegenerative disorders is important as individual treatments vary depending on the condition.
Jordan's syndrome (JS) or PPP2R5D-related intellectual disability is a rare autosomal dominant neurodevelopmental disorder caused by de novo mutations in the PPP2R5D gene. [2] Children with JS may also have epilepsy or meet criteria for diagnosis with autism spectrum disorder. [3]
An experimental blood test that detected Parkinson’s disease in a preliminary study could become the first specific tool for diagnosing the devastating neurodegenerative condition, researchers ...
The test showed a 93% accuracy in detecting the biomarkers associated with the condition. Simple skin biopsy ‘could help diagnose Parkinson’s disease at earliest stages’ Skip to main content
Parkinsonism is a clinical syndrome characterized by the four motor symptoms found in Parkinson's disease: tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Parkinsonism gait problems can lead to falls and serious physical injuries. Other common symptoms include:
There's currently no cure for Parkinson's disease, but researchers say they could be on their way to identifying it via a simple breath test. Cambridge researchers say a small group of people ...
Pantothenate kinase-associated neurodegeneration (PKAN), formerly called Hallervorden–Spatz syndrome, [1] is a genetic degenerative disease of the brain that can lead to parkinsonism, dystonia, dementia, and ultimately death. Neurodegeneration in PKAN is accompanied by an excess of iron that progressively builds up in the brain.
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