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Immunoglobulin therapy is the use of a mixture of antibodies (normal human immunoglobulin) to treat several health conditions. [13] [14] These conditions include primary immunodeficiency, immune thrombocytopenic purpura, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease, certain cases of HIV/AIDS and measles, Guillain–Barré syndrome, and certain other infections when a ...
Anti-D is recommended as a first-line therapy for ITP, along with corticosteroids and intravenous immune globulin (IVIG). [ 20 ] [ 22 ] [WinRho SDF is an anti-D manufactured, distributed and marketed by Cangene in the US.
"Smallpox vaccine: contraindications, administration, and adverse reactions". American Family Physician. 68 (5): 889– 896. PMID 13678138. ProQuest 73658843. CDC Smallpox Home; Quick Guide to Preexposure Smallpox Vaccination; U.S. Food and Drug Administration – Vaccinia Immune Globulin Intravenous (Human) Supporting Documents older than ...
The first report of immunizing an animal of one species (guinea pig) against the immune cells of another species (mouse lymphocytes) was by Élie Metchnikoff in 1899. He reported injecting cells recovered from mouse lymph nodes into Guinea pigs and waiting for the immunization to result in the accumulation of anti-mouse antibodies in the Guinea pig blood.
Thymoglobulin (manufactured by Sanofi) is an anti-human thymocyte immunoglobulin preparation made of purified polyclonal antibodies derived from rabbits.While these antibodies have a variety of specificities, their main mechanism of immunosuppression is through depletion of T cells.
Efgartigimod alfa, sold under the brand name Vyvgart, is a medication used to treat myasthenia gravis. [3] [4] Efgartigimod alfa is a neonatal Fc receptor blocker and is a new class of medication. [4]
A Janus kinase inhibitor, also known as JAK inhibitor or jakinib, [1] is a type of immune modulating medication, which inhibits the activity of one or more of the Janus kinase family of enzymes (JAK1, JAK2, JAK3, TYK2), thereby interfering with the JAK-STAT signaling pathway in lymphocytes.
Infusions can be administered in three different forms: intravenously (IVIg), [26] subcutaneously (SCIg), and intramuscularly (IMIg). The administration of intravenous immunoglobulins requires the insertion of a cannula or needle in a vein, usually in the arms or hands. Because a highly concentrated product is used, IVIg infusions take place ...