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PSA grades millions of cards per year, many worth six or seven figures. Without insurance, collectors face significant financial risk if their cards are lost or damaged, despite PSA’s public assurances of security. The first significantly controversial card grade was in fact the first card ever graded by PSA. This was the T206 Honus Wagner ...
The Gleason grading system is used to help evaluate the prognosis of men with prostate cancer using samples from a prostate biopsy. Together with other parameters, it is incorporated into a strategy of prostate cancer staging which predicts prognosis and helps guide therapy. A Gleason score is given to prostate cancer based upon its microscopic ...
Despite skepticism about extreme statements made in the paper, Ioannidis's broader argument and warnings have been accepted by a large number of researchers. [7] The growth of metascience and the recognition of a scientific replication crisis have bolstered the paper's credibility, and led to calls for methodological reforms in scientific research.
Richard J. Ablin (May 15, 1940 – October 6, 2023) [1] was an American scientist, most notable for research on prostate cancer.According to the Wall Street Journal: . Richard Ablin, a professor of pathology at University of Arizona College of Medicine, discovered the prostate-specific antigen (PSA) in 1970, and for nearly as long, he has argued that it should not be used for routine screening.
However, more research is needed to determine the optimal protocols and long-term efficacy of this approach. [77] As research continues, electrochemotherapy may offer new hope for prostate cancer patients, particularly those seeking less invasive treatment options or those for whom traditional therapies have failed.
Grading in cancer is distinguished from staging, which is a measure of the extent to which the cancer has spread. Pathology grading systems classify the microscopic cell appearance abnormality and deviations in their rate of growth with the goal of predicting developments at tissue level (see also the 4 major histological changes in dysplasia).
Prostate cancer is a major topic of ongoing research. From 2016 to 2020, over $1.26 billion was invested in prostate cancer research, representing around 5% of global cancer research funds. [122] This places prostate cancer 10th among 18 common cancer types in funding per cancer death, and 9th in funding per disability-adjusted life year lost ...
Collectors Universe Inc. is an American company formed in 1986, now based in Santa Ana, California, which provides third-party authentication and grading services to collectors, retail buyers and sellers of collectibles. Its authentication services focus on coins, trading cards, sports memorabilia, and autographs.