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  2. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs) were the first drugs to be developed for the treatment of depression, dating back to the early 1950s. Because of their undesirable adverse-effect profile and high potential for toxicity , due to their non-selective pharmacological effects, strict regimens were needed for ...

  3. Depressant - Wikipedia

    en.wikipedia.org/wiki/Depressant

    Tetrabamate is a controversial drug that is a combination of febarbamate, difebarbamate, and phenobarbital. It is marketed in Europe and has been largely, but not completely, discontinued. On 4 April 1997, after over 30 years of use due to reports of hepatitis and acute liver failure, the use of the drug was restricted. Carisoprodol, known as ...

  4. Antidepressant - Wikipedia

    en.wikipedia.org/wiki/Antidepressant

    Use of opioids and amphetamines for depression was later restricted due to their addictive nature and side effects. [268] [196] Extracts from the herb St John's wort have been used as a "nerve tonic" to alleviate depression. [270]

  5. Sertraline - Wikipedia

    en.wikipedia.org/wiki/Sertraline

    Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]

  6. Pseudodysphagia - Wikipedia

    en.wikipedia.org/wiki/Pseudodysphagia

    It is important that dysphagia (difficult or painful swallowing) be ruled out before a diagnosis of pseudodysphagia is made. Fear of choking is associated with anxiety, depression, panic attacks, hypochondriasis, and weight loss. The condition can occur in children and adults, and is equally common in men and women.

  7. Evolutionary models of human drug use - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_models_of...

    Researchers [39] suggest that because variation in drug use susceptibility is in part due to genetic factors, drug consumption could potentially be a costly and honest signal of biological quality. [ 40 ] [ 41 ] The hypothesis being that humans engage in substance use despite health costs in part to evidence that they can afford to do so.

  8. Orally disintegrating tablet - Wikipedia

    en.wikipedia.org/wiki/Orally_disintegrating_tablet

    Common among all age groups, dysphagia is observed in about 35% of the general population, as well as up to 60% of the elderly institutionalized population [12] [13] and 18-22% of all patients in long-term care facilities [14] ODTs may have a faster onset of effect than tablets or capsules, and have the convenience of a tablet that can be taken ...

  9. Management of depression - Wikipedia

    en.wikipedia.org/wiki/Management_of_depression

    The depression is multifactorial and has been on the increase due to societal pressure, genetic association and increase in use of drugs (Zhang et al. 2016) [full citation needed]. incorporation of nursing in management of depression may seem important in that nursing hold a pivotal role in health care delivery where they are they are the ...