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All articles undergo a rigorous peer review and are selected based on the originality of the findings, the superior quality of the work described, and the clarity of presentation. In 2021, the Journal of Hepatology had an impact factor of 30.083. [7] The Journal of Hepatology also publishes EASL's Clinical Practice Guidelines. [8]
Gut bacteria, bacterial endotoxins, and microbial debris transported to the liver from the gastrointestinal tract via the portal vein will first come in contact with Kupffer cells, the first immune cells in the liver. It is because of this that any change to Kupffer cell functions can be connected to various liver diseases such as alcoholic ...
Fatty liver disease (FLD), also known as hepatic steatosis and steatotic liver disease (SLD), is a condition where excess fat builds up in the liver. [1] Often there are no or few symptoms. [ 1 ] [ 2 ] Occasionally there may be tiredness or pain in the upper right side of the abdomen . [ 1 ]
Virchows Archiv: European Journal of Pathology is a monthly peer-reviewed medical journal of all aspects of pathology, especially human pathology. It is published by Springer Science+Business Media and an official publication of the European Society of Pathology .
Gastrointestinal pathology (including liver, gallbladder and pancreas) is a recognized sub-specialty discipline of surgical pathology.Recognition of a sub-specialty is generally related to dedicated fellowship training offered within the subspecialty or, alternatively, to surgical pathologists with a special interest and extensive experience in gastrointestinal pathology.
Liver diseases, including conditions such as non-alcoholic fatty liver disease (NAFLD), alcohol-related liver disease (ALD), and viral hepatitis, are significant public health concerns worldwide. In the United States, NAFLD is the most common chronic liver condition, affecting approximately 24% of the population, with the prevalence rising due ...
However, knowledge about liver disease in antiquity is questionable. Most of the important advances in the field have been made in the last 50 years. [when?] In 400 BC Hippocrates mentioned liver abscess in aphorisms. [3] Roman anatomist Galen thought the liver was the principal organ of the body. He also identified its relationship with the ...
The function and role of quiescent hepatic stellate cells is unclear. Recent evidence suggests a role as a liver-resident antigen-presenting cell, presenting lipid antigens to and stimulating proliferation of NKT cells. [7] When the liver is damaged, stellate cells can change into an activated state.