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Most individuals with G6PD deficiency are asymptomatic.When it induces hemolysis, the effect is usually short-lived. [5]Most people who develop symptoms are male, due to the X-linked pattern of inheritance, but female carriers can be affected due to unfavorable lyonization or skewed X-inactivation, where random inactivation of an X-chromosome in certain cells creates a population of G6PD ...
G6PD converts G6P into 6-phosphoglucono-δ-lactone and is the rate-limiting enzyme of the pentose phosphate pathway. Thus, regulation of G6PD has downstream consequences for the activity of the rest of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase is stimulated by its substrate G6P.
The Philippines, [f] officially the Republic of the Philippines, [g] is an archipelagic country in Southeast Asia.In the western Pacific Ocean, it consists of 7,641 islands, with a total area of roughly 300,000 square kilometers, which are broadly categorized in three main geographical divisions from north to south: Luzon, Visayas, and Mindanao.
This is a list of regions and highly urbanized cities of the Philippines by GDP and GDP per capita according to the data by the Philippine Statistics Authority. [ 1 ] [ 2 ] Data for 2023 estimates (international US$ using 2023 PPP conversion factor from the International Monetary Fund ).
This is a list of regions and provinces of the Philippines by Human Development Index (HDI) as of 2024. [1] The HDI is a statistic composite index of life expectancy, education (mean years of schooling completed and expected years of schooling upon entering the education system), and per capita income indicators, which is used to rank countries into four tiers of human development.
This is a complete list of cities and municipalities in the Philippines. The Philippines is administratively divided into 82 provinces ( Filipino : lalawigan ). These, together with the National Capital Region , are further subdivided into cities (Filipino: lungsod ) and municipalities (Filipino: bayan ).
For instance, 1st class cities have an income of ₱ 400 million or more, while 6th class cities earn less than ₱ 80 million in a four-year period. Each city is governed by both the Local Government Code of 1991 [2] and the city's own municipal charter, under the laws of the Philippines.
This is a list of terms which are used, or have been used in the past, to designate the residents of specific provinces of the Philippines. These terms sometimes overlap with demonyms of ethnic groups in the Philippines, which are also used as identifiers in common parlance. [1] * denotes an endonym, i.e., a name from the area's indigenous ...