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In biochemistry, denaturation is a process in which proteins or nucleic acids lose folded structure present in their native state due to various factors, including application of some external stress or compound, such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), agitation and radiation, or heat. [3]
Nucleic acid melting curve showing hyperchromicity as a function of temperature. Hyperchromicity is the increase of absorbance (optical density) of a material.The most famous example is the hyperchromicity of DNA that occurs when the DNA duplex is denatured. [1]
Denaturation (biochemistry), a structural change in macromolecules caused by extreme conditions; Denaturation (fissile materials), transforming fissile materials so that they cannot be used in nuclear weapons; Denaturation (food), intentional adulteration of food or drink rendering it unfit for consumption while remaining suitable for other uses
Nucleic acid thermodynamics is the study of how temperature affects the nucleic acid structure of double-stranded DNA (dsDNA). The melting temperature (T m) is defined as the temperature at which half of the DNA strands are in the random coil or single-stranded (ssDNA) state.
Denaturation Mapping is a form of optical mapping, first described in 1966. It is used to characterize DNA molecules without the need for amplification or sequencing . It is based on the differences between the melting temperatures of AT-rich and GC-rich regions. [ 1 ]
Biogeography is the study of the distribution of species and ecosystems in geographic space and through geological time.Organisms and biological communities often vary in a regular fashion along geographic gradients of latitude, elevation, isolation and habitat area. [1]
Map of Cape Cod showing shores undergoing erosion (cliffed sections) in yellow, and shores characterized by marine deposition (barriers) in blue. [1]Deposition is the geological process in which sediments, soil and rocks are added to a landform or landmass.
The shape of a state is determined by the political boundaries and geography that determine its territory, and that shape impacts the politics and economies of the state. [1] The six categories of state shapes are: compact; elongated or attenuated; fragmented; prorupted or protruded; perforated; and compound or complex. [2] [3] [4]